Titlebook: Chirurgisches Forum 2008; für experimentelle u M. D. Menger,R. Arbogast (Direktor der chirurgisch Conference proceedings 2008 Springer-Verl

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Increment

Der Verlust von CD3-zeta in Tumor-infiltrierenden T-Zellen ist ein negativer Prognosemarker für das CD8-cells was significantly larger in colon cancer specimens than in liver metastases (p < 0.05). However, liver metastases revealed significantly more NK-cells and B-cells (p = 0.01). CD3-zeta(ζ) was used as a marker of activation of T-cells. Clusters of tumour cells showed a significant loss of CD

CULP

戰(zhàn)勝

Bedeutung der TNFα-abh?ngigen Fas/FasL-Zytotoxizit?t für die hepatozellul?re Apoptose im Modell des se (497 ± 106 U/L) which was almost completely prevented by application of the soluble TNFα-receptor (apoptotic hepatocytes/mm.: 19 ± 4; ALT: 103 ± 19 U/L). Fas lpr/lpr mice revealed markedly lower FasL upregulation and were significantly protected against Gal/LPS-induced apoptosis (apoptotic hepato

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智力高

In vivo Analyse der humanen synovialen Mikrozirkulation bei Gonarthrose: Interaktion von Mikrozirkule SM was performed in 6-10 regions. SF was transcapsularily aspirated for ELISA-analysis of VEGF, MMP1+3, TIMP2, PGE2. SM biopsies were harvested for histolog. graduation of synovialitis. .: Radiographics in OA-knees revealed 0,3,10,5, and 2 patients for Ahlbaeck-stage 1,2,3,4, and 5. WOMAC score wa

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Microarray-basierte Analysen der genomischen Kopienzahl und der Genexpression beim Kolonkarzinomcancer tissue of 17/ 32 samples (foldchange . > 1,5). Patients with an amplification of 13q31.3 showed an overexpression of C13orf25 in 15 out of 22 patients (Foldchange . = 1,9) compared to samples with normal copy number and no overexpression of C13orf25. Known chromosomal amplification and overex

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Die überexpression der onkogenen Kras-Mutation G12D im adulten Pankreas führt zur Entstehung von higore, at 6 weeks of age, tamoxifen was administered as once daily intraperitoneal injection for a period of 5 days. Thirty mice were generated from each cohort (.-.ERT2; LSL-Kras. and .-.ERT2; LSL-Kras.), and groups of five mice were harvested at two-monthly intervals, beginning at 2 months post-tamo

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高調(diào)

Die Expression von Foxp3 in Pankreascarzinomzelllinien wird durch TGF-β2 funktionell reguliert und vrating lymphocytes were detected. Treatment of pancreatic cancer cell lines with TGF-β2 but not TGF-β1 led to an up regulation of Foxp3 mRNA and protein expression. In line with these findings we found that anti-TGF-β2 treatment resulted in Foxp3 down regulation. In co-culture assays of Panc89 cells