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Titlebook: Chemotherapy and Radiotherapy of Gastrointestinal Tumors; Hans Otto Klein Book 1981 Springer-Verlag Berlin Heidelberg 1981 Chemotherapy.Ra

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書(shū)目名稱Chemotherapy and Radiotherapy of Gastrointestinal Tumors
編輯Hans Otto Klein
視頻videohttp://file.papertrans.cn/225/224968/224968.mp4
叢書(shū)名稱Recent Results in Cancer Research
圖書(shū)封面Titlebook: Chemotherapy and Radiotherapy of Gastrointestinal Tumors;  Hans Otto Klein Book 1981 Springer-Verlag Berlin Heidelberg 1981 Chemotherapy.Ra
描述Attempts to influence survival of patients with colorectal cancer (CRC) by adjuvant chemotherapy are limited by the variability of survival in different prognostic groups [4] and the paucity of drugs that have shown activity in the advanced disease [10]. Of the few drugs which are active in the advanced disease, only 5-fluorouracil (5-FU) and razoxane ?±1,2-bis(3,4-dioxopiperazin-1-yl)propane) are suitable for long-term adjuvant treatment [2, 9]. 5-FU has been widely and intensively studied as adjuvant chemotherapy in CRC [7], but there is no unanimity that it has even the marginal influence on survival that has been claimed [3, 10]. Razoxane has not previously been tested for adjuvant or maintenance treatment in CRC. It has however a number of biological activities which might be thought useful in the treatment of residual or minimal tumours [1] and which might therefore make it useful as an adjuvant. Thus it specifically prevents tumour dissemination and metastases in some tumours and normalizes the neovasculature which the tumours induce [6, 8, 11]. The drug is not cytotoxic in the usual sense, does not affect non-dividing cells, and only blocks cell division during a brief peri
出版日期Book 1981
關(guān)鍵詞Chemotherapy; Radiotherapy; Tumor; Tumors; therapy; Radiaton Oncology
版次1
doihttps://doi.org/10.1007/978-3-642-81681-9
isbn_softcover978-3-642-81683-3
isbn_ebook978-3-642-81681-9Series ISSN 0080-0015 Series E-ISSN 2197-6767
issn_series 0080-0015
copyrightSpringer-Verlag Berlin Heidelberg 1981
The information of publication is updating

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https://doi.org/10.1007/978-3-642-19146-61973. There are now 39 institutions in the Netherlands, Germany, Switzerland, Italy, Spain, France, Israel, and Belgium contributing to the various clinical trials. They have already registered 1,350 patients, of whom 950 are evaluable for the studies. Seven clinical trials are still in progress or
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https://doi.org/10.1007/978-3-642-19199-2” surgery alone often proves inadequate, many types of postoperative adjuvant procedures have been applied in an attempt to improve the long-term survival rates. Systemic adjuvant therapy generally consists of either chemotherapy or immunotherapy, and after radical surgery, the 5-year survival rates
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On a Change of SU(3) into Three SU(2),U(1)azoxane. Thirty-one patients were Duke’s group A; 49 group B; 61 group C; and 17 group D; an additional four patients were randomized in error..The adjuvant group received the usual clinical care and 125 mg razoxane twice daily for 5 consecutive days (Monday–friday) every week indefinitely. Control
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https://doi.org/10.1007/978-3-642-19199-2new cases of malignant RS tumors were diagnosed; of these, 1,103 were in males, representing 6% of all male malignant tumors (incidence per 100,000 = 22.6). In females, 864 new cases were diagnosed, representing 5.1% of all female tumors (incidence per 100,000 = 16.3).
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On a Change of SU(3) into Three SU(2),U(1)orouracil (5-FU) [31, 32]. Furthermore, the reported long serum half-life of ftorafur of approximately 10–16 h for the beta-phase [1, 4, 10, 19, 20] makes the drug interesting for split-dose schedules. In comparison with single daily injections, split-dose administration of a drug with a long serum
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Geometrical Properties of the U(1) Gaugeexpected. For this reason a comparative pharmacokinetic study of intravenous versus oral application was performed on six patients, as well as a pilot study on 13 patients with adenocarcinomas of different origins. The results show that 5-FU is absorbed rapidly. The biological availability increases
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