Titlebook: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide; Philip K. Moore,Matt Whiteman Book 2015 The Editor(s) (if applicable) and Th

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Queer Children, Crooked Houses,e, and inflammation is now believed to be responsible for several disease conditions. Research in our laboratory has shown that hydrogen sulfide (H.S) acts as a novel mediator of inflammation. At present, work in several research groups worldwide is focused on determining the role of H.S in inflamma

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https://doi.org/10.1007/978-3-319-33852-1erest was observed in H.S biology in the last two decades. The scientific community has succeeded to unravel many important physiological and pathological effects of H.S on mammalian body systems. Thus, H.S is now referred to as a third endogenous gaseous mediator along with nitric oxide and carbon

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Hans-Friedrich K?hn,Chia-Yi Chiureceptor potential ankyrin-1 (TRPA1). Intraplantar and intracolonic administration of H.S donors promotes somatic and visceral pain, respectively, via activation of Ca.3.2 and TRPA1 in rats and/or mice. Injection of H.S donors into the plantar tissues, pancreatic duct, colonic lumen, or bladder caus

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Howard M. Wiseman,Eric G. Cavalcantis of H.S in the pathophysiology of cancer have emerged. This is particularly evident in cancers of the colon and ovaries, where the malignant cells both overexpress cystathionine-β-synthase (CBS) and produce increased amounts of H.S, which enhances tumor growth and spread by (a) stimulating cellular

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H2S Synthesizing Enzymes: Biochemistry and Molecular Aspectsetase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST). These enzymes are constitutively present in a wide array of biological cells and tissues and their expression can be induced by a number of disease states. It is becoming increasingly clear that H.S is an important mediator of a wide rang

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