| 書目名稱 | Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide | | 編輯 | Philip K. Moore,Matt Whiteman | | 視頻video | http://file.papertrans.cn/225/224886/224886.mp4 | | 概述 | A recently discovered biological entity attracting growing interest from academics worldwide.Plays key roles in normal physiological processes whilst aberrant biosynthesis can lead, or contribute to, | | 叢書名稱 | Handbook of Experimental Pharmacology | | 圖書封面 |  | | 描述 | This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit. | | 出版日期 | Book 2015 | | 關(guān)鍵詞 | biosynthesis; disease; hydrogen sulfide; mechanisms; molecular biology; physiology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-18144-8 | | isbn_softcover | 978-3-319-35909-0 | | isbn_ebook | 978-3-319-18144-8Series ISSN 0171-2004 Series E-ISSN 1865-0325 | | issn_series | 0171-2004 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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