Titlebook: Chemical Mutagens; Principles and Metho Frederick J. Serres,Alexander Hollaender Book 1982 Springer Science+Business Media New York 1982 DN

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Zhenyu Yan,He Yang,Yu Xi,G. P. Rameshal mutagens and carcinogens. The most important hepatic activation system is the cytochrome-P-450-dependent monooxygenase system. This system, which can catalyze a diverse range of reactions (e.g., epoxidation, hydroxylation, dealkylation, and oxidative cleavage), generates highly reactive electrophiles in the process..

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Jun Zheng,Yue Ma,Mengyao Yu,Changhua Heher at the Fungal Genetics Stock Center USA (for a list of the stocks, see Barratt ..). Thus, the majority of strains . can be considered isogenic except for the known mutations and silent mutations carried by a particular strain.

出汗

Metabolic Activation Systems , for Carcinogen/Mutagen Screening Tests,ogenic activity of numerous chemicals to their capacity to be converted into electrophilic derivatives, which can react with DNA and other cellular macromolecules and therefore exert a mutagenic effect, has led to the suggestion that there may be a formal relationship between carcinogenesis and mutagenesis..

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內(nèi)部

,—An Organism for Detecting a Range of Genetic Damage,her at the Fungal Genetics Stock Center USA (for a list of the stocks, see Barratt ..). Thus, the majority of strains . can be considered isogenic except for the known mutations and silent mutations carried by a particular strain.

Prostatism

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ooks in this series have provided a mechanism for the publication of many important new developments in the study of the genetic effects of environmental chemicals. This series was launched by Dr. Alexander Hollaender who, beginning in 1971, edited Volumes 1-4 and then coedited Volumes 5-7. The success of his978-1-4615-6625-0

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David R. Hayhurst,S. Hinduja,A W Labibc judgment of genetic impact on an exposed population. This is particularly germane to the issue of using data derived from somatic-cell studies to conclude that an agent will produce genetically recoverable events in germ cells.

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