Titlebook: Characterization of Nanoparticles Intended for Drug Delivery; Jeffrey D. Clogston,Rachael M. Crist,Stephan T. St Book 2024Latest edition L

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Characterization of Nanoparticles Intended for Drug Delivery978-1-0716-3786-9Series ISSN 1064-3745 Series E-ISSN 1940-6029

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Nanoparticle Size Distribution and Stability Assessment Using Asymmetric-Flow Field-Flow Fractionati ideal nor thoroughly descriptive enough to define the full complexity of these materials. Asymmetric-flow field-flow fractionation (AF4) with various in-line detectors, such as ultraviolet–visible (UV–vis), multi-angle light scattering (MALS), refractive index (RI), and DLS, is an alternative techn

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Measuring Size and Number Concentration of Metallic Nanoparticles Using spICP-MStry (ICP-MS) in single-particle (sp) mode. Accurately determining the size of individual nanoparticles on a per-particle basis, both quickly and accurately, is an ever-increasing need within nanoparticle characterization. ICP-MS is capable of measuring a broad range of metallic nanoparticle sizes wi

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Ion Quantitation in Liposomal Products Using RP-HPLC with Charged Aerosol Detectiongs is challenging due to the absence of chromophores or fluorophores of ions and the efficiency of their release from the liposome structure. To address these issues, a method based on reversed-phase high-performance liquid chromatography (RP-HPLC) coupled with a charged aerosol detector (CAD) has b

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Current Considerations and Practical Solutions for Overcoming Nanoparticle Interference with LAL Assproducts. Endotoxin contamination of engineered nanomaterials and nanotechnology-based medical products represents a significant translational hurdle. Nanoparticles often interfere with an in vitro limulus amebocyte lysate (LAL) assay commonly used in the pharmaceutical industry for the detection an