| 書(shū)目名稱 | Central D1 Dopamine Receptors |
| 編輯 | Menek Goldstein,Kjell Fuxe,Irving Tabachnick |
| 視頻video | http://file.papertrans.cn/224/223175/223175.mp4 |
| 叢書(shū)名稱 | Advances in Experimental Medicine and Biology |
| 圖書(shū)封面 |  |
| 描述 | The development of a selective D1 dopamine (DA) receptor antagonist SCH 23390 stimulated a number of studies on the functions mediated by central DA receptor subtypes. It was generally assumed that the central D1 DA receptor isa molecular entity whose function awaits further discovery. The papers presented in this volume clearly show that this is no longer the case and that D1 DA receptors have many behavioral fuctions which might be altered in pathological states. A number of papers have recognized the interdependence of the regulatory functions of the D1 DA receptors with D2 and other receptor proteins, and vice versa. The biochemical, pharmacological and morphological characterization of the D1 and D2 DA receptor binding proteins, as well as of DARPP-32, illustrates the complex interactions between various macromolecules. Procedures described for the purification of the D1 and D2 DA receptor subtypes are fundamental for future studies on the mechanisms involved in the coupling of the receptor proteins with signal transducing systems. Several studies in this volume show that D1 DA receptors have behavioral functions and that they are often similar to the responses mediated by D2 |
| 出版日期 | Book 1988 |
| 關(guān)鍵詞 | biochemistry; interaction; interdependence; media; physiology; proteins; regulation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4899-2723-1 |
| isbn_softcover | 978-1-4899-2725-5 |
| isbn_ebook | 978-1-4899-2723-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
|Archiver|手機(jī)版|小黑屋|
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