| 書目名稱 | Cellular and Molecular Biology of Intermediate Filaments | | 編輯 | Robert D. Goldman,Peter M. Steinert | | 視頻video | http://file.papertrans.cn/224/223091/223091.mp4 | | 圖書封面 |  | | 描述 | Research activity on intermediate filaments (IF) has increased dramatically over the past decade. For the most part, this surge of interest is due to their identification as ubiquitous constituents of the cytoskeleton and karyoskeleton (nuclear matrix) of eukaryotic cells and the fact that we know very little regarding their functions. In sharp contrast to the other major cytoskeletal systems, microfilaments and microtubules, IF exhibit a high degree of heterogeneity with regard to their protein subunit composition. Indeed, one can only marvel at the number of different IF polypeptides, their associated proteins (IFAP) and, consequently, the number of genes involved in encoding the multiple constituents of the various IF networks found in different cell types. The chapters in this book demonstrate how various experimental approaches involv- ing cellular, molecular, biochemical, and immunological methods have been utilized to generate information regarding the structure and function of IF. To this end, we have gathered together chapters from experts in the major fields of IF research. In each chapter, the authors have combined reviews of the available scientific literature with thei | | 出版日期 | Book 1990 | | 關鍵詞 | Polypeptide; biology; cell nucleus; development; evolution; genes; molecular biology; protein; proteins | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4757-9604-9 | | isbn_softcover | 978-1-4757-9606-3 | | isbn_ebook | 978-1-4757-9604-9 | | copyright | Springer Science+Business Media New York 1990 |
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