Titlebook: Cellular Factors Involved in Early Steps of Retroviral Replication; John A. T. Young (The Howard M. Temin, Professor i Book 2003 The Edito

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Book 2003of retroviral replication. A better understanding of these functions will provide critical new insights into retrovirus-host cell interactions and is likely to prove useful for the future development of effective antiretroviral therapies..

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, zwischen ?Vollendung und Verw?sserung??,m, after association of the virus with cognate receptors at the cell surface. This process is mediated by viral fusion proteins anchored in the viral envelope and can be defined based on the requirement for low pH to trigger membrane fusion. In viruses that utilize a pH-dependent entry mechanism, su

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?… volkstümlich nach Form und Inhalt …?y facilitate many gene therapy applications. The surface glycoproteins of membrane-enveloped viruses stand among the choice candidates to control the target cell receptor recognition and host range of retroviral vectors onto which they are incorporated. This can be achieved in many ways, such as the

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Zum Musiktheater der Neuen Sachlichkeitein player in retroviral integration is the viral integrase, which enters the cell as part of the virus. Although purified integrase protein is necessary and sufficient to perform the basic catalytic DNA breakage and joining steps of retroviral integration, a variety of normal cellular proteins have

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https://doi.org/10.1007/978-3-642-19012-4Retroviral Replication; Reverse Transcription Complex; Virion Adsorption; cell; retroviruses; virus