Titlebook: Cell Cycle Checkpoints; Methods and Protocol Willis X. Li Book 2011 Springer Science+Business Media, LLC 2011 DNA damage checkpoints.apopto

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書目名稱Cell Cycle Checkpoints影響因子(影響力)




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Methods for Studying the G2 DNA Damage Checkpoint in Mammalian Cells,epaired. This is a common response to a variety of DNA damaging agents, including ionizing radiation and many chemotherapeutic agents used in the treatment of cancer. The G2 DNA damage checkpoint acts to inhibit the mitotic cyclin-dependent kinase, and thus cells are arrested in the G2 phase of the

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Evaluating Spindle Assembly Checkpoint Competence in Mouse Oocytes Using Immunoblotting, of the anaphase-promoting complex or cyclosome (APC/C), the SAC sets the timing of anaphase-onset by co-ordinating the timely destruction of key proteins with the completion of chromosome alignment. How mammalian oocytes regulate chromosome segregation during the first meiotic division (meiosis I)

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Studying Cell Cycle Checkpoints Using , Cultured Cells, vitro system instead of a whole organism has two main advantages: it saves time and simple and effective molecular techniques are available. It has been shown that . cells, similarly to mammalian cells, display cell cycle checkpoint pathways required to survive DNA damaging events (de Vries et al.

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Using , Larval Imaginal Discs to Study Low-Dose Radiation-Induced Cell Cycle Arrest,nuing to cycle. . larval epithelial sacs, called imaginal discs, are an excellent in vivo model system for studying radiation-induced cell cycle arrest. Larval imaginal discs go into cell cycle arrest after being subjected to low-dose irradiation, are subject to easy genetic manipulation, are not cr

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