Titlebook: Cell Culture in the Neurosciences; Jane E. Bottenstein,Gordon Sato Book 1985 Plenum Press, New York 1985 biochemistry.brain.cell.cells.dev

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On the Mysteries of Unemploymentut the sequence of events that constitute neuronal development, neuroblasts become postmitotic, migrate, extrude neurites that follow tortuous but precise paths throughout the organism, and finally establish synaptic contacts among themselves and with nonneuronal target tissues. In addition, maturat

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On the Mysteries of Unemployment differentiation of cells in the CNS. Evidence has accumulated suggesting that hormones are involved in this critical process. After the discovery of the association of hypothyroidism with mental retardation, thyroidectomy of rats at birth was found to produce irreversible morphological changes with

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https://doi.org/10.1007/978-94-015-8080-9uroectodermal origin and are initially localized in a midline position along the entire neuraxis. Later in development, they migrate into the embryo, home into various locations, and differentiate. They contribute to the cranial nerves V, VII, IX, and X, and they give rise to autonomic ganglia, nerv

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https://doi.org/10.1007/978-94-015-8100-4it allows one to obtain large amounts of cells corresponding to the very early stages of neural differentiation, and second, since teratocarcinoma stem cells [embryonal carcinoma (EC) cells] can differentiate into other cell types, it offers the opportunity to study the segregation of the neuronal l

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https://doi.org/10.1007/978-94-015-8100-4simplification and reductionism will be involved. It has been evident from the earliest experiments in cell culture that neural properties are expressed in culture and that application of this technique to appropriate questions could give highly instructive results. We wish to discuss one approach t

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https://doi.org/10.1007/978-94-015-8100-4networks, namely the membrane excitability of the individual elements and the process of intercellular communication of “information” into and throughout the CNS. Neurophysiology is often divided into two broad areas of investigation. One involves quantitative analysis of the basic membrane mechanis