Titlebook: Cell Aging: Molecular Mechanisms and Implications for Disease; Christian Behl,Christine Ziegler Book 2014 The Editor(s) (if applicable) an

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Book 2014extended life spans in animal models. Linking these different determinants of aging with disease, this volume aims to reveal their multiple interdependencies. We see that there is no single “perfect” theory of aging and that instead it is possible to define what the authors call the .molecular aging

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Aging and Cell Aging: An Introduction,rson born today has a high statistical chance to reach the age of 100, to become a centenarian. Since aging is the primary risk factor for many human disorders it is mandatory to understand the aging process and how it affects onset and course of disorders of the elderly. Scientifically the medium l

hypnogram

Cell Cycle: The Life Cycle of a Cell,It describes a series of events leading to cell division and duplication and can be sectioned into phases that are controlled by a collection of proteins interacting with each other, the cyclines and the cycline-dependent kinases. It is mandatory that DNA replication is conservative meaning that its

LATHE

Theories and Mechanisms of Aging,no unifying theory of aging. The individual theories put individual factors and processes in focus and for each theory there are direct links to life span or to age-related disorders. In the following chapter, the key theories of aging focusing on telomeres, DNA damage, oxidative stress as well as p

LATHE

Selected Age-Related Disorders,igate and understand the link between aging as key risk factor and single syndromes. In some chapters of this book links have been identified between molecular mechanisms of aging and the pathogenesis of human disorders in the elderly. Here, the focus is put on Alzheimers disease (AD) and cancer. Wh

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Book 2014 by different endogenous and exogenous factors. Since aging is a major risk factor in connection with a variety of human disorders, it is increasingly becoming a central topic in biochemical and medical research. The plethora of theories on aging – some of which have been discussed for decades – are

Mendicant

On the (Im)Possibility of Business Ethicshs and years until it is eventually dying or exchanged. The majority of our nerve cells is never replaced. Understanding cellular aging and its influence on human disease is a key challenge of molecular medicine research.