Titlebook: Case Studies in Bayesian Statistics; Volume IV Constantine Gatsonis,Robert E. Kass,Mike West Conference proceedings 1999 Springer Science+B

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Modeling Customer Survey Datarmance of the company on many attributes ranging from product quality and technology to pricing and sales support. The data discussed in this paper are from a quarterly survey run at Lucent Technologies..We have built a Bayesian model for the data that is partly hierarchical and has a time series co

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The Bayesian approach to Population pharmacokinetic/pharmacodynamic modelingns in the body and efficacy/toxicity. Understanding this relationship leads to the determination of doses which are both effective and safe. Population pharmacokinetic/pharmacodynamic models provide an important aid to this understanding..Pharmacokinetics considers the absorption, distribution and e

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Longitudinal Modeling of the Side Effects of Radiation Therapyue side effects. A recent clinical trial undertaken by the Eastern Cooperative Oncology Group made a study of toxic reactions in patients receiving hyperfractionated accelerated radiation therapy (HART). 28 lung cancer patients were observed over a four week time period during which the radiation th

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Validating Bayesian Prediction Models: a Case Study in Genetic Susceptibility to Breast Cancergenes, BRCA1 and BRCA2, been identified. Though rare, mutation of a gene at either locus is associated with a much increased risk of developing breast as well as ovarian cancer. Understanding this risk is an important element of medical counseling in clinics that serve women who present with a famil

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Mixture Models in the Exploration of Structure-Activity Relationships in Drug Design Pharmaceutical research laboratories developing test compounds for screening synthesize many related candidate compounds by linking together collections of basic molecular building blocks, known as monomers. These compounds are tested for biological activity, feeding in to screening for further ana