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Titlebook: Cardiovascular Specific Gene Expression; Pieter A. Doevendans,Robert S. Reneman,Marc Bilsen Book 1999 Springer Science+Business Media Dord

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書目名稱Cardiovascular Specific Gene Expression
編輯Pieter A. Doevendans,Robert S. Reneman,Marc Bilsen
視頻videohttp://file.papertrans.cn/222/221988/221988.mp4
叢書名稱Developments in Cardiovascular Medicine
圖書封面Titlebook: Cardiovascular Specific Gene Expression;  Pieter A. Doevendans,Robert S. Reneman,Marc Bilsen Book 1999 Springer Science+Business Media Dord
描述Improving our insights into the genetic predisposition to cardiovascular disease is one of the most important challenges in our field in the next millennium, not only to unravel the cause of disease but also to improve the selection of patients for particular treatments. Nowadays, for example, subjects with a cholesterol above a particular plasma level are exposed to a cholesterol lowering regime based upon the beneficial outcome of epidemiological studies which include subjects not prone to the disease, despite a plasma cholesterol above the accepted level. Identification of the patients who are genetically predisposed to the consequences of this disorder will reduce the number of subjects unnecessarily treated and, hence, the costs of health care. Because in most cardiovascular diseases the genetic component is a consequence of more than one gene defect, only limited progress has as yet been made in identifying subjects genetically at risk. For example, in hypertension only in less than 10% of the patients the genetic defect has been identified. It has been known for quite some time that in heart and blood vessels fetal genes are as high blood pressure and upregulated or induced
出版日期Book 1999
關(guān)鍵詞Chromosom; Promoter; cardiovascular; cardiovascular system; development; gene expression; gene therapy; gen
版次1
doihttps://doi.org/10.1007/978-94-015-9321-2
isbn_softcover978-90-481-5189-9
isbn_ebook978-94-015-9321-2Series ISSN 0166-9842
issn_series 0166-9842
copyrightSpringer Science+Business Media Dordrecht 1999
The information of publication is updating

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Equations Governing Fluids in?Motion of SM22a have been described that make this gene a promising candidate [3,10]. Marker proteins are not only important as molecules that allow a better definition of SMC variants, but also because they may provide promoter sequences that can be used as instruments to manipulate gene expression in SM
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https://doi.org/10.1007/978-3-030-73788-7t growth, septation, and remodelling of these distinct cardiac segments result in the development of separate right and left atrial and ventricular chambers with independent inlets and outlets. Morphological remodelling between different cardiac sub-domains is often perturbed in congenital heart def
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Seismic Analysis of Pine Flat Concrete Damyocardium. However, during development the predominant isoform expressed is slow skeletal troponin I [2]. We have previously documented aspects of troponin expression in the human heart [3–6] and demonstrated a developmental switch in troponin I expression during human development. Analysis of mRNA
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Optimizing Electromagnetic DevicesAV-node, the top of the AV-bundle and the top of the bundle branches. This is true for both neonatal and adult rat heart. By contrast, Cx40 exibits a clearly different expression pattern [2]. During embryonic development, Cx40 expression is widespread throughout the myocardium, but is gradually down
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Variational Finite Element Methodf inherited cardiac arrhythmias: the Long QT Syndrome (LQTS) [1] and the Brugada Syndrome [2]. In the cases of these diseases identified mutations in ion channel structure have been shown to cause functional changes in channel properties using heterologous expression of the channel proteins [3]. The
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