Titlebook: Cardiac Glycosides 1785–1985; Biochemistry — Pharm Erland Erdmann,K. Greef,J. C. Skou Conference proceedings 1986 Springer-Verlag Berlin He

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Nonsmooth Analysis and Control TheoryDigitalis has been known since the Middle Ages and used mainly by external application. Oral application, however, was mentioned before William Withering..The priority of publication of the use of digitalis in dropsy is discussed between William Withering and Erasmus Darwin.

PRISE

Analysis of Generalized Derivatives,The paper briefly surveys the recent state of the authors’ research into the biochemical basis for the targeted synthesis of cardiac glycosides with selective action.

cauda-equina

Therapeutic use of digitalis until the time of William WitheringDigitalis has been known since the Middle Ages and used mainly by external application. Oral application, however, was mentioned before William Withering..The priority of publication of the use of digitalis in dropsy is discussed between William Withering and Erasmus Darwin.

Obituary

Biochemical basis for the targeted synthesis of cardiac glycosides with selective actionThe paper briefly surveys the recent state of the authors’ research into the biochemical basis for the targeted synthesis of cardiac glycosides with selective action.

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盡忠

Proximal Calculus in Hilbert Space,ress the subject of digitalis therapy and all its problems. Not only was he a prominent expert in this field, but he had also studied the history of digitalis in the last years of his life. Unfortunately he died in 1981. Therefore, Professor Kurt Greeff (born 1920) and I published some time ago a sh

anesthesia

Discrete Approximations in Optimal Control,lar Ca. concentration is markedly affected by the balance between Na.,K.-ATPase activity (capacity of the sodium pump) and Na. influx rate. The sodium pump in cardiac muscle has a substantial reserve capacity under normal conditions; however, a relatively modest sodium pump inhibition or an increase

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Ji?i Outrata,Michal Ko?vara,Jochem Zowehe interaction of cardiac glycosides with Na/K-ATPase of intact myocardium were quantitatively considered and combined: 1. Cardiac glycoside binding depends on the turnover rate of Na/K-ATPase, and 2. occupation and inhibition of a fraction of Na/K-ATPases by cardiac glycoside leads to an increased