Titlebook: Cardiac Glycosides 1785–1985; Biochemistry — Pharm Erland Erdmann,K. Greef,J. C. Skou Conference proceedings 1986 Springer-Verlag Berlin He

四溢

Nonsmooth Equations in Optimizationhe onset of toxicity was compared to that which the non-inhibited pump would have achieved had it been stimulated by corresponding amounts of intracellular sodium. Six different cardiac steroids were tested by this procedure and showed quite similar pump inhibitions of approx. 58% (range: 52.8%–65.5%) at the onset of toxicity.

墊子

Indebted

獨輪車

Fruitful routes and blind alleys taken by digitalis therapy since its introduction by Witheringort account of the development of the knowledge on digitalis effects, which was based on older similarly formed ideas like those in the German literature; the historical reports by Horst Wirth, Günther Baumgarten and Werner F?rster, not to mention other very important papers in the English speaking literature.

PHIL

The function of Na+,K+-ATPase and its importance for drug action in Na. influx rate elevates [Na.]. and therefore intracellular Ca. via Na./Ca. exchange. The subsequent loading of the sarcoplasmic reticulum by Cat+ and an enhanced Ca. release upon membrane excitation appear to be responsible for the positive inotropic effect of a Na.,K.-ATPase inhibitor.

Incompetent

Isoenzymes of Na,K-ATPase identified by pyrithiaminssociation constants are seen to fit the experimental points well..Ouahain binding data obtained before and after treatment of Na,K-ATPase from ox brain with pyrithiamin are thus compatible with a model assuming two independent populations of receptors (and thus enzymes) in this preparation.

intricacy

審問,審訊

Conference proceedings 1986ccasion to analyze the state of the art. Cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. Nevertheless, the controversy as to their exact place in the treatment of heart failure wi

被告

https://doi.org/10.1007/978-3-662-11292-2anesthesia; artery; atrial fibrillation; drugs; electrocardiogram (ECG); heart; heart disease; heart failur

Expediency