Titlebook: Cardiac Glycoside Receptors and Positive Inotropy; Evidence for more th E. Erdmann Conference proceedings 1984 Dr. Dietrich Steinkopff Verl

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Nonradioactive Analysis of Biomolecules obtained at a K. = 2.6 x 10. mol/1 (about 40% of the binding sites) whereas a low affinity, high capacity binding was established at a KD = 1.3 x 10. mol/1 (about 60% of the binding sites). Similar results were obtained when studying the effect of increasing Na.-concentrations on ouabain binding: a

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https://doi.org/10.1007/978-3-662-00144-8) and digoxin (dg-gluc). The parent compounds digitoxin (dt) and digoxin (dg) were studied for comparison and all compounds were also investigated in guinea-pig isolated papillary muscles. All compounds increased myocardial force of contraction in human preparations in a concentration-dependent mann

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https://doi.org/10.1007/978-3-642-72376-6Stent; arrhythmia; cardiology; cardiovascular; circulation; drugs; heart; heart failure; pharmacodynamics; re

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978-3-642-72378-0Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt — Production: Holger Frey 1984