Titlebook: Cardiac Bioelectric Therapy; Mechanisms and Pract Igor R. Efimov,Mark W. Kroll,Patrick J. Tchou Book 20091st edition Springer-Verlag US 200

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The Generalized Activating Functionbe the similarities among nerve, brain, and cardiac stimulation). More recently, studies of cardiac cell cultures grown in user-designed patterns. have permitted detailed investigations of electric field-induced responses of linear strands,. intercellular cleft spaces,. fiber branches, expansions an

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ZEST

Critical Points and the Upper Limit of Vulnerability for Defibrillationentricular fibrillation (VF) is induced when the shock is given during cardiac repolarization (i.e., the vulnerable period). The lower limit of this range, the ventricular fibrillation threshold (VFT), is considerably lower than the range of shock strengths that defibrillate. However, the upper limi

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The Role of Shock-Induced Nonregenerative Depolarizations in Ventricular Fibrillation and Defibrillaks, the disease is advancing … and death is near.”. Heartbeat irregularities as a marker of disease were also recognized and described in ancient China as can be deduced from a conversation between the “Golden Emperor” Huang Ti and his physician Ch‘i Pai (circa 2600 BC) “When the pulse beats are lon

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Commentary

The Role of Microscopic Tissue Structure in Defibrillationearch would have higher chances for success if it were guided by the exact knowledge of the defibrillation mechanism. Significant advances in understanding defibrillation were made in recent years using sophisticated electrical and optical mapping techniques as well as advanced mathematical models o

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The Virtual Electrode Hypothesis of Defibrillationcal side effects.. Therefore, reduction of defibrillation energy is highly desirable. However, the basic mechanisms of defibrillation still remain debatable a century after its inception, which has slowed further improvement of the therapy. This chapter explores one of the leading hypotheses of defi