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Titlebook: Captopril and Hypertension; David B. Case,Edmund H. Sonnenblick,John H. Laragh Book 1980 Springer Science+Business Media New York 1980 blo

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書(shū)目名稱Captopril and Hypertension
編輯David B. Case,Edmund H. Sonnenblick,John H. Laragh
視頻videohttp://file.papertrans.cn/222/221506/221506.mp4
叢書(shū)名稱Topics in Cardiovascular Disease
圖書(shū)封面Titlebook: Captopril and Hypertension;  David B. Case,Edmund H. Sonnenblick,John H. Laragh Book 1980 Springer Science+Business Media New York 1980 blo
描述This monograph was developed from a collection of papers that were origi- nally presented at a symposium entitled "Pathogenesis of Hypertension" held at the Henry Chauncy Conference Center, Princeton. New Jersey. These manuscripts were subsequently revised, updated, and reorganized in a manner suitable for this publication. The symposium was planned to stimu- late interest among investigators and clinicians alike in the potential for a new class of drugs called converting enzyme inhibitors in clinical medicine. The meeting was sponsored by the Squibb Institute for Medical Research, whose pioneering biochemical and pharmaceutical research had led to the development of the first orally active converting enzyme inhibitor. It is hoped that this monograph will cohesively pull together the thesis that the identification, quantification, and containment of the renin factor in hypertension can be a powerful diagnostic and therapeutic strategy in clinical medicine. In addition, the sequence of studies presented in this manuscript will serve to demonstrate how basic biochemical and physio- logical research produces fundamental and critical information on which subsequent major advances in cl
出版日期Book 1980
關(guān)鍵詞blood pressure; development; drugs; hypertension; medicine; pathogenesis; pharmacology; research
版次1
doihttps://doi.org/10.1007/978-1-4615-9179-5
isbn_softcover978-1-4615-9181-8
isbn_ebook978-1-4615-9179-5
copyrightSpringer Science+Business Media New York 1980
The information of publication is updating

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Nuffield College and Norman Chesterrious organ systems in amounts appropriate to their needs is accomplished by constriction or relaxation of vascular smooth muscle. Within this closed system, a pressure gradient is discerned, with pressure greatest in the aorta and lowest in the vena cavae.
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Western Transformation after the Cold Wardifference between the rise of plasma renin activity on standing compared with the slower increase under the influence of sodium deprivation. In examining the situation in normal man, it is important to try to incorporate the findings from various other types of experimental studies, ranging from th
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https://doi.org/10.1007/978-1-349-26959-4sis via angiotensin’s control of aldosterone release on the other. A number of lines of evidence have accumulated over the last decade which point to a central role for angiotensin in the normal control of the renal cir-culation. and in the pathogenesis of a variety of diseases that involve the kidn
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Western Transformation after the Cold Warmportant roles in maintenance of cardiovascular homeostasis and contribute to the elevation of arterial blood pressure in various hypertensive disease states.. The immediate product of the action of angiotensin-converting enzyme is the octapeptide, angiotensin II, the most potent naturally occurring
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https://doi.org/10.1007/978-0-230-23366-9-converting enzyme (ACE) [E.C. 3.4.15.1] has also been designated as converting enzyme (CE), peptidyldipeptide carboxy hydrolase, kininase II, or “bradykininase.” Hence, in vivo inhibition of ACE will reduce the pressor activity of AI, but not that of AII, and augment the vasodepressor activity of b
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