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Titlebook: Cancer and Zebrafish; Mechanisms, Techniqu David M. Langenau Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive lic

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發(fā)表于 2025-3-21 16:50:11 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Cancer and Zebrafish
副標題Mechanisms, Techniqu
編輯David M. Langenau
視頻videohttp://file.papertrans.cn/222/221238/221238.mp4
概述Provides the most up-to-date research on zebrafish models for oncogene and tumor suppressor discovery.Explores potential drug targets in various cancers, including leukemia, melanoma, pancreatic and l
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Cancer and Zebrafish; Mechanisms, Techniqu David M. Langenau Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive lic
描述Thisvolume focuses on defining the unique attributes of using the?zebrafish cancermodel for discovering important pathways and potential drug targets for thetreatment of human cancers. Using the?zebrafish model, the volumeexplores?oncogene and tumor suppressor discovery, chemical genetic approaches,genomics, epigenetics, cancer imaging, and cell transplantation. Contributedchapters come from the most?prominent laboratories working in this field, whichprovides a unique perspective on?zebrafish models from a wide spectrum of theresearch community. In addition, the book offers a detailed analysis of the mostcurrent research in the area for specific?zebrafish cancer models, including Tcell leukemia, rhabdomyosarcoma, liver and?pancreatic cancer, melanoma,neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. Achapter is also dedicated to the development and utilization of other piscinemodels of cancer. The compilation of chapters in the volume culminates into acomprehensive and definitive text on?zebrafish and cancer, providing a muchneeded resource on the powerful attributes of the?zebrafish model system..
出版日期Book 2016
關(guān)鍵詞cancer models; germ cell tumors; oncogenes; tumor suppressors; xenograft transplantation
版次1
doihttps://doi.org/10.1007/978-3-319-30654-4
isbn_softcover978-3-319-80860-4
isbn_ebook978-3-319-30654-4Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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https://doi.org/10.1007/b102415r genomic noise and ultimately uncover central drivers of malignancy. Finally, I discuss downstream analytic tools, including network analysis, that can help to organize the alterations into coherent biological frameworks that can then be investigated further.
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The Toolbox for Conditional Zebrafish Cancer Modelseactive proteins will enable the development of even more sophisticated zebrafish cancer models. Here, we introduce this growing toolbox of conditional transgenic approaches, discuss its current application in zebrafish cancer models and provide an outlook on future perspectives.
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Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discoverygh the functional analysis of cancer genomes. Now in the second decade, zebrafish cancer models are poised for even faster growth as they are used in high-throughput genetic analyses to elucidate key mechanisms underlying critical cancer phenotypes.
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發(fā)表于 2025-3-23 00:54:56 | 只看該作者
0065-2598 ious cancers, including leukemia, melanoma, pancreatic and lThisvolume focuses on defining the unique attributes of using the?zebrafish cancermodel for discovering important pathways and potential drug targets for thetreatment of human cancers. Using the?zebrafish model, the volumeexplores?oncogene
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Selected Applications of Geostatical Methods open the door for complex genetic analysis of tumorigenesis. In this chapter, we will describe the various technologies for conducting genome editing in zebrafish with special emphasis on the approaches to inactivate genes.
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