書目名稱 | Cancer Stem Cells in Solid Tumors |
編輯 | Alison L. Allan |
視頻video | http://file.papertrans.cn/222/221200/221200.mp4 |
概述 | Focuses specifically on the role of CSCs in solid cancers.Written by active investigators with research programs related to oncology and/or stem cell biology and leaders in their field.Provides a comp |
叢書名稱 | Stem Cell Biology and Regenerative Medicine |
圖書封面 |  |
描述 | .The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requirement for a specific “niche”/microenvironment to grow; and an increased capacity for self-protection against harsh environments, toxins, and drugs. .?.Cancer Stem Cells in Solid Tumors. represents a detailed overview of cancer stem cells and their role in solid cancers. Comprised of 24 chapters, this volume will provide readers with a comprehensive understanding of this important and evolving field..?.Topics covered include:.Introduction of the CSC hypothesis.Historical perspectives and the contr |
出版日期 | Book 2011 |
關鍵詞 | Allan; Cancer; Cell; Solid; Stem; Tumor |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-61779-246-5 |
isbn_softcover | 978-1-61779-758-3 |
isbn_ebook | 978-1-61779-246-5Series ISSN 2196-8985 Series E-ISSN 2196-8993 |
issn_series | 2196-8985 |
copyright | Springer Science+Business Media, LLC 2011 |