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Titlebook: Cancer Risks; Strategies for Elimi Peter Bannasch Conference proceedings 1987 Springer-Verlag Berlin Heidelberg 1987 cancer.cancer research

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書目名稱Cancer Risks
副標(biāo)題Strategies for Elimi
編輯Peter Bannasch
視頻videohttp://file.papertrans.cn/222/221191/221191.mp4
圖書封面Titlebook: Cancer Risks; Strategies for Elimi Peter Bannasch Conference proceedings 1987 Springer-Verlag Berlin Heidelberg 1987 cancer.cancer research
描述A large body of information about possible causes of cancer has been ac- cumulated by both clinical experience in man and observations in animal experiments. There is general agreement that in most cases cancer is due to exogenous factors, albeit the genetic disposition may also play an impor- tant part. Three main categories of exogenous risk factors have been iden- tified, namely chemicals, radiation, and viruses. In principle, it should be possible to prevent cancer by eliminating such risk factors. However, in spite of the rapidly growing number of well established risk factors, many shortcomings in our understanding of the causes of human cancer and in the introduction of effective preventive measures are evident. In addition to obvious gaps in our scientific knowledge, inadequacies in personal life style, irresponsible handling of environmental contaminants, and in some areas also deficiencies in political decisions seriously hamper the elimina- tion of risk factors for cancer. It was this background which prompted the Committee coordinating Cancer Research in the GroBforschungseinrichtungen in the Federal Re- public of Germany to organize a conference on Strategies for the E
出版日期Conference proceedings 1987
關(guān)鍵詞cancer; cancer research; epidemiology; prevention
版次1
doihttps://doi.org/10.1007/978-3-642-71843-4
isbn_softcover978-3-540-17465-3
isbn_ebook978-3-642-71843-4
copyrightSpringer-Verlag Berlin Heidelberg 1987
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Assessment of Cancer Risk from Chemicalse the unequivocal establishment of viruses as cancer-causing agents (Rous 1911). Percival Pott (1775) is generally credited with having described the first chemically induced occupational cancer, in chimney sweepers after long-term exposure to soot, followed later on by reports of coal tar being cau
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Validity of Short-Term Tests to Detect Carcinogenic Chemicalshelp evaluate the effect of the numerous chemicals in the human environment. The use of these tests has been extensively discussed (Hollstein et al. 1979). Discussion has focused on the significance of the biological end-points and the capacity for metabolic activation. Further aspects of in vitro t
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Preneoplastic Lesions as Indicators of the Carcinogenic Risk Caused by Chemicalsduced in whole animals up to the present. A great disadvantage of this approach is the long lag period in the development of neoplasms produced with chemicals. In order to overcome this drawback, many efforts have been made to detect early biochemical or morphological lesions which might be specific
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Chemical Carcinogens in TobaccoSchairer and Schoeniger in Jena in 1943 were among the first reports to indicate an increased risk for lung cancer among smokers. However, it was not until 1950 that the evidence from case-control studies in the UK and the USA directed attention towards the association of cigarette smoking with lung
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Primary Prevention of Tobacco-Related Canceripe smoking. However, it was not until the twentieth century that the enormous rise in lung cancer elicited serious interest as a tobacco-related problem. As we reflect upon this history, we need to appreciate that a monograph on lung cancer written by Adler in 1912 included the question: “Is it wor
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