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Titlebook: Cancer Metastasis — Related Genes; Danny R. Welch Book 2002 Springer Science+Business Media Dordrecht 2002 cancer.cancer research.carcinom

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書目名稱Cancer Metastasis — Related Genes
編輯Danny R. Welch
視頻videohttp://file.papertrans.cn/222/221154/221154.mp4
叢書名稱Cancer Metastasis - Biology and Treatment
圖書封面Titlebook: Cancer Metastasis — Related Genes;  Danny R. Welch Book 2002 Springer Science+Business Media Dordrecht 2002 cancer.cancer research.carcinom
描述Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control of the metastatic process at the molecular level. This volume begins to explore our current knowledge regarding the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all of the authors attempted to put their findings into a context for translation to the clinical situation, the state-of-the-art does not fully allow this. Nonetheless, we write these summaries of our work as an early effort toward that end. I am grateful to all of the authors who have contributed generously of their time and energies to make this volume a reality. To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors. Unless cells accomplish every step of the met
出版日期Book 2002
關(guān)鍵詞cancer; cancer research; carcinoma; cell; genes; melanoma; metastasis; proliferation; protein; translation; tu
版次1
doihttps://doi.org/10.1007/0-306-47821-8
isbn_softcover978-94-017-3922-1
isbn_ebook978-0-306-47821-5Series ISSN 1568-2102 Series E-ISSN 2215-1648
issn_series 1568-2102
copyrightSpringer Science+Business Media Dordrecht 2002
The information of publication is updating

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Autocrine Motility Factor and Its Receptor as Regulators of Metastasis, about characterization of AMF and AMFR will be needed to increase our understanding of the fundamental processes which control motility in mammalian cells and provide the basis for the development of more effective clinical treatments and specificmodalities which inhibit rumor cell motility in vitr
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Nm23 Metastasis Suppressor Gene, low metastatic potential. Transfection of . into metastatically competent melanoma and breast, oral squamous cell and colon carcinoma cell lines reduced tumor metastatic potential upon . injection. No effect on primary tumor size was observed, making . a metastasis suppressor gene. Research in Dros
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The Role of KISS1 in Melanoma Metastasis Suppression, if not for the subsequent complications of distant metastatic foci. Compounding this notion are statistics revealing that the number of cases of malignant melanoma have doubled each of the last four decades (1) and autopsies of patients presenting with melanoma reveal lung invasion in approximately
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