Titlebook: Cancer Cytogenetics; Methods and Protocol Thomas S.K. Wan Book 2017 Springer Science+Business Media, LLC, part of Springer Nature 2017 Arra

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Book 2017rposes. The chapters in this book cover topics such as chromosome preparation for myeloid malignancies; chromosome bandings; fluorescence in situ hybridization probe preparation; array-based comparative genomic hybridization; and cytogenetic nomenclature and reporting. The updated reviews on chromos

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Chromosome Bandings, for identifying heterochromatin by denaturing chromosomes in a saturated alkaline solution followed by Giemsa staining. Different banding techniques may be selected for the identification of chromosomes.

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High Resolution Fiber-Fluorescence In Situ Hybridization,g a brief review of this technology, including its major development and increasing applications, typical protocols to generate DNA/chromatin fiber will be described, coupled with rationales, as well as technical tips. These released DNA/chromatin fibers are suitable for an array of cytogenetic/cytogenomic analyses.

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1064-3745 ation advice from the experts.Includes supplementary materia.This volume provides readers with detailed protocols covering the main cancer cytogenetics techniques needed for clinical utilization and research purposes. The chapters in this book cover topics such as chromosome preparation for myeloid