Titlebook: Cancer Cytogenetics; Methods and Protocol John Swansbury Book 20031st edition Humana Press 2003

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Cytogenetic Studies in Hematologic Malignancies,ity. It was once thought that poor morphology alone, even in the absence of detectable abnormality, might be sufficient to identify a malignant clone. However tempting this explanation has been to anyone who has seen such coexisting populations, such a hypothesis has not been subsequently confirmed.

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FISH Techniques,tory. It is possible to study air-dried bone marrow or blood films, fresh tumor touch prints, and wax-embedded sections of solid tumors. The techniques are very similar to those described here (.,.). It is also possible to perform FISH studies on preparations that have already been banded and analyz

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Solving Problems in Multiplex FISH,resents a useful tool for the genome-wide screening of chromosome rearrangement and is becoming increasingly practiced in both the research and diagnostic professions. It follows that a chapter on the use of these technologies is appropriately included in a series on the methods used in malignancy c

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Shu-Hua Zhang,Xin-Fu Zhou,Robert A. Rushity. It was once thought that poor morphology alone, even in the absence of detectable abnormality, might be sufficient to identify a malignant clone. However tempting this explanation has been to anyone who has seen such coexisting populations, such a hypothesis has not been subsequently confirmed.

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https://doi.org/10.1007/978-94-017-7509-0often of poor morphology, and tend to be involved in complex and subtle rearrangements; in such cases, conventional cytogenetic studies are unable to define fully the entire karyotype. This limitation has been overcome by the introduction of new techniques, known as . hybridization (ISH), which bind

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Helmut Madersbacher,Jerzy B. Gajewskitory. It is possible to study air-dried bone marrow or blood films, fresh tumor touch prints, and wax-embedded sections of solid tumors. The techniques are very similar to those described here (.,.). It is also possible to perform FISH studies on preparations that have already been banded and analyz

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