Titlebook: Cancer Biology and Therapeutics; Joseph G. Cory,Andor Szentivanyi Book 1987 Springer Science+Business Media New York 1987 cancer treatment

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Biological and Clinical Implications of the Stem Cell Concept in Human Malignancyt for carcinogenesis is the stem cell population. Much of the support for the former view is based on study of transplantable tumors in animals while the importance of cell differentiation has been reinforced mostly by study of spontaneous animal or human tumors.

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Sugar Analogs and 5-Fluorouridine in Combination Chemotherapyluorouracil, 5-f luorodeoxyuridine, or 5-fluorouridine (1). Inhibition of thymidylate synthase can lead to a depletion of thymine nucleotides and result in DNA synthesis inhibition due to substrate deficiency.

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Clinical Cancer Treatment and Drug Resistance: The Interface of the Clinic and the Laboratory patients receiving systemic cancer treatment. In this volume we seek to give an overview of known molecular and clinical factors which may result in cancer drug resistance and the probable interplay of these factors in the evolution of resistance in man. Finally, we discuss treatment approaches tha

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Nitrosamines and Human Cancer: Some Implications of Basic Researchnd biological activities, which include cytotoxicity, carcinogenicity, mutagenicity, teratogenicity and use in the chemotherapy of human cancer, have been extensively reviewed (1–7). Most studies of the acute toxicity of the nitrosamines have been carried out with the shorter chain dialkyl and simpl

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ce, Hungary, West Germany, and of course, the United States. The congeniality of the participants promoted the friendly exchange of knowledge which, it is hoped, will greatly hasten the time when successful management of human cancer will become routine. Future symposia in this series will be highly focused a978-1-4757-9566-0978-1-4757-9564-6

Homocystinuria

Cost Benefits of Rehabilitation Programs,ned. For DNA, these are nucleotide sequences with enhanced susceptibility to intercalating or covalent-binding agents; specificity of these sites, however, is usually not stringent. Substrate-binding sites on enzymes offer better possibilities for specificity. Some insight into the dimensions of the