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Titlebook: Buruli Ulcer; Mycobacterium Ulcera Gerd Pluschke,Katharina R?ltgen Book‘‘‘‘‘‘‘‘ 2019 The Editor(s) (if applicable) and The Author(s) 2019 C

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樓主: T-Lymphocyte
51#
發(fā)表于 2025-3-30 09:15:39 | 只看該作者
Paul P. B. Eggermont,Vincent N. LaRicciahly pathogenic for humans appears to be the acquisition of a plasmid, bearing genes encoding polyketide synthases and polyketide-modifying enzymes involved in the biosynthesis of a unique macrolide toxin, named mycolactone. The cytotoxic and immunosuppressive properties of mycolactone account for mu
52#
發(fā)表于 2025-3-30 12:43:38 | 只看該作者
53#
發(fā)表于 2025-3-30 20:06:18 | 只看該作者
P. P. B. Eggermont,V. N. LaRicciacal possum population and then spills over to humans living nearby. Biting insects, particularly mosquitoes, are likely mechanical vectors but there may be other pathways of transmission involved. Universal?access to rapid diagnosis with PCR and availability of combination oral antibiotic therapy an
54#
發(fā)表于 2025-3-30 23:01:26 | 只看該作者
P. P. B. Eggermont,V. N. LaRicciation in the occurrence of BU and possibly of the number of bacteria in the environment. Therefore, although there are not many cases of BU in Japan, studying them will shed light on the bacteriological and clinical aspects of BU.
55#
發(fā)表于 2025-3-31 01:18:02 | 只看該作者
https://doi.org/10.1007/978-1-0716-1244-6and B [6, 7] (Fig. 1). Since the initial discovery of mycolactone A/B, eight additional mycolactone congeners have been identified that are either produced by . strains of different geographical origins or genetically related fish and frog pathogens, which were initially given different species desi
56#
發(fā)表于 2025-3-31 08:23:58 | 只看該作者
Luis J. Alías,Paolo Mastrolia,Marco Rigoliew antimicrobial compounds or vaccine candidates for BU. The histopathological appearance of the lesions and the spreading of the bacteria to the lymph nodes, however, are quite different to what is observed in the human disease. In order to overcome these disadvantages, the pig as a model for BU wa
57#
發(fā)表于 2025-3-31 09:40:25 | 只看該作者
https://doi.org/10.1007/978-1-4612-5282-5ar appearance is high. With the introduction of combination antibiotic therapy, replacing excision surgery as the standard treatment for BU, pre-treatment confirmation of the clinical diagnosis has further gained in importance to avoid the redundant use of anti-mycobacterial drugs. At present, avail
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