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Titlebook: Breast Cancer Metastasis and Drug Resistance; Challenges and Progr Aamir Ahmad Book 2019Latest edition Springer Nature Switzerland AG 2019

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發(fā)表于 2025-3-21 19:15:20 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Breast Cancer Metastasis and Drug Resistance
期刊簡(jiǎn)稱Challenges and Progr
影響因子2023Aamir Ahmad
視頻videohttp://file.papertrans.cn/191/190565/190565.mp4
發(fā)行地址Provides comprehensive information on breast cancer disease, the factors that make it lethal, and current research progress.Excellent source of reference for students/beginning researchers as well as
學(xué)科分類Advances in Experimental Medicine and Biology
圖書(shū)封面Titlebook: Breast Cancer Metastasis and Drug Resistance; Challenges and Progr Aamir Ahmad Book 2019Latest edition Springer Nature Switzerland AG 2019
影響因子.Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of?.Breast Cancer Metastasis and Drug Resistance.?brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Expertsalso discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients wi
Pindex Book 2019Latest edition
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Health and Racial Disparity in Breast Cancer,cts more than one in ten women worldwide. The chance for a female to be diagnosed with breast cancer during her lifetime has significantly increased from 1 in 11 women in 1975 to 1 in 8 women (Altekruse, SEER Cancer Statistics Review. 1975–2007. National Cancer Institute, Bethesda, 2010). This chanc
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,Breast Cancer: Current Perspectives on the?Disease Status, has shown that the past and ongoing research has an enormous implication in improving the clinical outcome in breast cancer. This has been attributed to the progress made in the realm of screening, diagnosis and therapeutic strategies engaged in breast cancer management. However, poor prognosis in
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,Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the?Same Coin,s. Although autophagy is mainly accepted as a cell survival mechanism, it also modulates the process known as “type II cell death”. AKT/mTOR pathway is an upstream activator of autophagy and it is tightly regulated by the ATG (autophagy-related genes) signaling cascade. In addition, wide ranging cel
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Breast Cancer Heterogeneity in Primary and Metastatic Disease, of relapse and overall survival. Traditional histopathological classification aims to categorise tumours into subgroups to inform clinical management decisions, but the diversity within these subgroups remains considerable. Application of massively parallel sequencing technologies in breast cancer
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Bone Metastasis of Breast Cancer,ncer patient. Clinically, complications secondary to bone metastasis include pain, pathologic fractures, spinal cord compression, and hypercalcemia of malignancy. Because bone metastasis is extremely common in patients with metastatic breast cancer, clinical management of bone metastases is an impor
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Therapeutic Options for Metastatic Breast Cancer,mportant to develop therapies that go beyond those that just provide palliation of symptoms. Currently, there are several types of therapies available to help treat breast cancer including: hormone therapy, immunotherapy, and chemotherapy, with each one depending on both the location of metastases a
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