Titlebook: Breast Cancer Management for Surgeons; A European Multidisc Lynda Wyld,Christos Markopoulos,El?bieta Senkus-Ko Textbook 2018 Springer Inter

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Breast Cancer Epidemiologycidence of breast cancer in the developed world but a greater mortality from breast cancer in the developing world. Within Europe, variation of incidence and mortality are present. This is due to a complex combination of factors including risk factors, limitations of data and much inequality in the

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Hereditary Breast Cancer Genetics and Risk Prediction Techniquesisk. Increased familial breast cancer risk is also observed in families testing negative for high-risk germline mutations, suggesting that polygenic interactions of multiple lower-penetrance susceptibility alleles, in addition to traditional breast cancer risk factors, are important causes of famili

猛然一拉

Screening for High-Familial-Risk Womenontralateral malignancy. Therefore, additional surveillance has been recommended to reduce risks. Mammography, ultrasound and magnetic resonance imaging (MRI) are the three modalities that have been evaluated as screening tools for these women. Breast MRI is the most sensitive screening modality in

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Risk-Reducing Breast and Ovarian Surgery for Women at High Familial Riskereditary increased risk for breast and ovarian cancer. In this chapter, the efficacy of surgical interventions, the indications for surgery and different surgical techniques are discussed. Health-related quality of life outcomes such as body image changes, physical and sexual wellbeing and psychoso

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Molecular Profiling of Breast Cancer and DCISuiding adjuvant treatment decisions. MGAs differ in terms of the technological platform used, the specific genes assessed and the patient populations in which they were developed and validated. This chapter provides an overview of currently available MGAs and discusses several studies that compare r

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