Titlebook: Breast Cancer Biology for the Radiation Oncologist; Jonathan Strauss,William Small,Gayle E. Woloschak Book 2015 Springer-Verlag Berlin Hei

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艦旗

Desert

Current Clinical Role of Genetic Profiling in Breast Cancer, Several genetic profile assays are already commercially available, and others are being developed and tested. OncotypeDx, a 21-gene assay, and MammaPrint, a 70-gene assay are the most extensively evaluated tests. Currently, three prospective trials to assess the predictive value of gene signature a

BADGE

glowing

Cancer Stem Cells and Radiotherapy,lation due to radiation described decades ago is being supported by new experimental data. The heterogeneity of cancer cell populations in a given tumor is recently evidenced by the present of cancer stem cells (CSCs) that are different from other non-CSC tumor cells and maintain unique self-renewal

巧辦法

隱藏

Genetic Syndromes and Radiotherapy in Breast Cancer,ely recent identification of the BRCA1 and BRCA2 genes in the mid-1990s, the expense associated with testing, and the inherent selection biases, the available literature has inherent limitations with relatively small patient numbers and lack of prospective randomized trials in this subset of patient

神經(jīng)

Experimental Therapies in Breast Cancer,therapy is designed to maximize therapeutic potential while minimizing harm to surrounding healthy tissue. Recently, advances in material design, synthesis, and characterization have lead to a surge in the number of approaches intended to shrink or eliminate the tumor burden of breast cancer. These

絕緣

A Volatile Mix of Business and Politicsthat the candidate gene approach is inadequate to discover clinically useful indicators of radiation sensitivity. Genome-wide association studies (GWAS) and international collaborations may hold the key to future progress in this area.

endocardium

From Outcast to Presidential Premiers in molecular-based and gene-based targeting, intralesional and intraoperative designs, and, importantly, the expanding sphere of nanomaterials. The topic of nanoscale materials will be developed to include approaches of organic-based systems, inorganic-based systems, and biological hybrid nanomaterials.