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Titlebook: Brain Imaging in Substance Abuse; Research, Clinical, Marc J. Kaufman (Assistant Professor of Psychiatry Book 2001 Springer Science+Busine

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發(fā)表于 2025-3-21 19:45:27 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Brain Imaging in Substance Abuse
期刊簡(jiǎn)稱Research, Clinical,
影響因子2023Marc J. Kaufman (Assistant Professor of Psychiatry
視頻videohttp://file.papertrans.cn/191/190187/190187.mp4
學(xué)科分類Forensic Science and Medicine
圖書封面Titlebook: Brain Imaging in Substance Abuse; Research, Clinical,  Marc J. Kaufman (Assistant Professor of Psychiatry Book 2001 Springer Science+Busine
影響因子The last two decades have seen prodigious growth in the application of brain imaging methods to questions of substance abuse and addiction. Despite considerable advances in our understanding of the central effects of drugs provided by preclinical data, relatively little direct evidence was known of how substances of abuse affect the brain and other eNS processes in humans. Brain imaging techniques have allowed access to the human brain and enabled the asking of questions never before imagined. The positron emission tomography (PET) data ofVolkow and her colleagues in the late 1980s, showing the uptake and time course of cocaine‘s binding in the human brain, revealed for the first time the distinct sites of action of this drug. This work was extremely important because it showed clearly, through imaging a drug in the brain of a living human, that the time course of its action paralleled the behavioral state of "high. " This study marked a turning point in our understanding of drug-brain-behav- ior interactions in humans. Many more investigations of drug effects on the structure and function of the human brain were soon to follow, leading to much better insights into brain systems. B
Pindex Book 2001
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Book 2001nsiderable advances in our understanding of the central effects of drugs provided by preclinical data, relatively little direct evidence was known of how substances of abuse affect the brain and other eNS processes in humans. Brain imaging techniques have allowed access to the human brain and enable
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發(fā)表于 2025-3-22 09:54:53 | 只看該作者
R. Lavayssière,A. E. Cabée,R. A. Parientyuch methods, however, comes at the cost of considerable technological complexities that may hinder their appropriate application and interpretation. This chapter summarizes underlying principles, basic limitations, and varied applications of PET and SPECT as they apply to the field of substance abuse research.
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發(fā)表于 2025-3-22 16:30:04 | 只看該作者
White Matter Disorders-Myelination,hy (SPECT). These advances have led to the ability to non-invasively measure regional CBF and cerebral blood volume (CBV), the regional metabolism of glucose (CMRg1c) and oxygen (CMRO.), and the regional binding of radiolabeled compounds such as neurotransmitters and their analogs.
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Emission Tomographic Studies in Substance Abuse,hy (SPECT). These advances have led to the ability to non-invasively measure regional CBF and cerebral blood volume (CBV), the regional metabolism of glucose (CMRg1c) and oxygen (CMRO.), and the regional binding of radiolabeled compounds such as neurotransmitters and their analogs.
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發(fā)表于 2025-3-23 02:32:28 | 只看該作者
Electroencephalography, Topographic Mapping, and Event-Related Potentials in Substance Abuse Researthat an electrical signal occurred concurrently with nerve impulses. This observation motivated a British physiologist, Richard Caton, to demonstrate in 1875 that brains from animals also generated electrical impulses.
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