| 期刊全稱 | Bone Morphogenetic Proteins: Systems Biology Regulators | | 影響因子2023 | Slobodan Vukicevic,Kuber T. Sampath | | 視頻video | http://file.papertrans.cn/190/189699/189699.mp4 | | 發(fā)行地址 | Provides a good overview on the role of BMPs as regulators in Systems Biology?.Complements the first three volumes on BMPs in the series (BMPs-from laboratory to clinical practice; BMPs-regeneration o | | 學(xué)科分類 | Progress in Inflammation Research | | 圖書封面 |  | | 影響因子 | .This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes..This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.. | | Pindex | Book 2017 |
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