Titlebook: Bone Morphogenetic Proteins: Regeneration of Bone and Beyond; Slobodan Vukicevic,Kuber T. Sampath Book 2004 Springer Basel AG 2004 biology

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Bone morphogenetic protein receptors and their nuclear effectors in bone formation, identity of these morphogens which define skeletal patterning. With the advent of powerful methods for protein purification, capability to determine amino acid sequences on small amounts of protein and DNA cloning, bone morphogenetic proteins (BMPs) were discovered [.-.]. The amino acid sequences p

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Biology of bone morphogenetic proteins,he bone morphogenetic proteins (BMPs), with more than 20 members identified in organisms ranging from sea urchin to mammals. BMPs were first named by the ability to induce ectopic cartilage and endochondral bone when implanted in experimental animals [.]. It is now clear that the name is misleading

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Clinical experience of osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of l morbidity and impairment in individuals of both genders, all age groups and regardless of socioeconomic circumstances. On an annual basis, fractures account for over 36 million lost days from work, more than seven million days missed from school, approximately 6.4 million days of hospitalization, n

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Development of the first commercially available recombinant human bone morphogenetic protein (rhBMPlable. More than two decades after Urist’s first observation of demineralized bone osteoinductivity in 1965, a single bone morphogenetic protein was isolated from bone and produced recombinantly (rhBMP-2) [., .]. The recombinant production of BMP-2 opened the door for the development of a commercial

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