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Titlebook: Bone Metastasis and Molecular Mechanisms; Pathophysiology Gurmit Singh (Director of Research, Professor of P Book 2004 Springer Science+Bus

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發(fā)表于 2025-3-30 09:23:24 | 只看該作者
OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis, proteins helped to resolve numerous questions regarding the exact molecular mechanisms for bone resorption. These proteins also neatly account for the long-recognized dependence of osteoclasts on the osteoblast/stromal cell population. This pathway was rapidly elucidated after the discovery of oste
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發(fā)表于 2025-3-30 16:23:27 | 只看該作者
Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer,and mortality. They cause clinical disease due to extensive, intractable bone pain, pathological fractures, and spinal cord compression and leads eventually to death. 70% of patients that die of breast cancer have noticeable disease in their bones (1, 2). Similar numbers are found for prostate cance
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