Titlebook: Bone Marrow Transplantation; Basic and Clinical S Susumu Ikehara (Professor),Fumimaro Takaku (Presid Conference proceedings 1996 Springer-V

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Roles of Jak Kinases in Human GM-CSF Receptort the activation of She is not essential for . activation and several tyrosine residues coordinate to activate . activation..It is well documented that IL-3 or GM-CSF activates JAK in various cells. However the role of JAK2 in IL-3/GM-CSF functions is largely unknown. We examined the role of JAK2 in

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Susumu Ikehara (Professor),Fumimaro Takaku (Presid

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‘,’: The Paradox of , in Luther and Beyond cells over the next 3 weeks. The initial decrease appears to be mediated by IL-12-induced production of IFN-γ, possibly by natural killer cells and/or T cells which do not persist in these cultures. Studies in naive mice demonstrate a similar acute decrease in peripheral leukocyte count, mediated b

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‘,’: The Paradox of , in Luther and Beyondc progenitor cell fraction. These findings suggest the interaction of hematopoietic progenitor cells with HTKL-expressing cells in bone marrow and the involvement of HTKL in the differentiation and/or proliferation of these progenitor cells.

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https://doi.org/10.1057/978-1-137-59315-3s. As a source for collecting stem cells, cord blood is the least obtrusive for the donor. A limitation is the volume, with only a small proportion of the samples giving an adequate number of stem cells. While the cord blood samples with more than 5 x 10. cells are few in number, they are ready to b