Titlebook: Blood-Brain Barrier; Tatiana Barichello Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Neuronal progenitor c

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In Vitro BBB Models: Working with Static Platforms and Microfluidic Systems,e performed in vivo. However, major limitations of this approach, including limited translational significance to human patients, high cost, time, and labor to develop the appropriate model (e.g., transgenic or inbred models), have greatly favored the parallel development of in vitro models. These a

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STING

Transepithelial/Transendothelial Electrical Resistance (TEER) to Measure the Integrity of Blood-Bra in vitro cellular barriers for transport studies. TEER measurement has advantages over traditional permeability measurements as a quick, label-free, and non-invasive method. TEER measurement has an added advantage that it can be performed in real -time if the measurement electrodes are integrated i

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Cell-Penetrating Peptides as Theranostics Against Impaired Blood-Brain Barrier Permeability: Implicbstances. This dynamic barrier, which is primarily comprised of precisely arranged, specialized endothelial cells, astrocytes, and pericytes, not only prevents the brain interstitial fluid from mixing with the components of blood but also maintains a delicate balance between central nervous system (

Pelvic-Floor

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GRAIN

Zebrafish (,) as a Viable Model to Study the Blood-Brain Barrier,the BBB is a major obstacle for drug delivery into the brain. Under pathological conditions, the integrity of the BBB is susceptible to disruption and can be broken down in severe brain diseases. Therefore, the understanding of intrinsic complexity as well as modulation of the BBB is critical to dis

cyanosis

Evans Blue-Albumin as a Marker to Evaluate Blood-Brain Barrier Integrity in Neonatal and Adult Rodequires appropriate models and markers to demonstrate the integrity of the interface between the blood and the brain. Historically, dyes have been used to analyze the blood-brain barrier (BBB) mechanisms and for measurements of plasma volume. Despite some limitations, Evans blue is still the most com

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Experimental Tools to Study the Regulation and Function of the Choroid Plexus,h neurologic diseases, in newborns, young adults, and the elderly, like kernicterus, multiple sclerosis, and Alzheimer’s disease. Yet, the CP still remains an overlooked organ requiring further investigation..The minute size of the CP, particularly in rodent models, increases the difficulties associ

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