Titlebook: Blood Conservation in Cardiac Surgery; Karl H. Krieger (Professor and Vice Chairman),O. W Book 1998 Springer-Verlag New York, Inc. 1998 By

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Pharmacologic Approaches to Coagulation (Aprotinin, Epsilon Amino Caproic Acid, DDAVP, Tranexamic AcBleeding and blood transfusion have long been associated risks of open-heart surgery. The source of this risk is twofold, being related both to the hemodilution and the coagulopathy that have to the present time been inherent components of cardiopulmonary bypass (CPB). The prevention and treatment of coagulopathy is the focus of this chapter.

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Current Practice of Blood Transfusion in Cardiac Surgerylusion, and subsequently with the development of the heart lung machine, red blood cell transfusion and, later, component therapy have been intimately related to the successful evolution of cardiac surgery. In many large institutions, the activities of the cardiac service determined the majority of

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Preoperative Autologous and Directed Blood Donationn of a patient’s blood preoperatively for later use during the intraoperative and postoperative periods. Its appropriate application leads to a direct reduction in homologous transfusion requirement via a unit-for-unit substitution of autologous for homologous blood. Although there was a gradual inc

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AIDS Risk in Cardiac Surgery from practically every continent. In the United States, 80,961 AIDS cases were reported in 1994 alone and the cumulative AIDS cases since 1981 are over 440,000.. More importantly, it is estimated that 1 in 250 Americans is infected with the human immunodeficiency virus (HIV).. Although initial epid

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Hemostasis and the Effect of Cardiopulmonary Bypass on Hemostasisellular and biochemical mediators/activators to repair the injury. Concurrently opposing mediators/inhibitors are activated to locally limit the repair process, thus protecting the essential fluidity of the circulation. The call to clot is always accompanied by the message to temper the action. Duri