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Titlebook: Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach; Francesco Saverio De Ponte Book 2012 Springer-Verlag Italia 20

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發(fā)表于 2025-3-21 18:30:37 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach
影響因子2023Francesco Saverio De Ponte
視頻videohttp://file.papertrans.cn/189/188889/188889.mp4
發(fā)行地址First multidisciplinary text on the subject, by worldwide experts.Update of the latest advances, technical details, and expert advice regarding this subject.Presents multiple designs, explanatory figu
圖書封面Titlebook: Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach;  Francesco Saverio De Ponte Book 2012 Springer-Verlag Italia 20
影響因子During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today‘s oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts. When this unique binding process of bisphosphonates to bone occurs, osteoclasts are poisoned, and this reduces or eliminates bone turnover. Alveolar bone in the mandible and maxilla turns over more rapidly than in long bones, so the jaws are a better target for bisphosphonate toxicity. It wasn‘t until 2003 that today‘s intravenous and oral nitrogen-containing bisphosphonate medications were implicated as major risk factors in the development of exposed necrotic boneof the jaws. Most of the researchers who reported cases of bisphosphonate-induced osteonecrosis of the jaw found that these patients were treated with zoledronate, pamidronate, or a combination of thes
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沙發(fā)
發(fā)表于 2025-3-21 20:37:51 | 只看該作者
板凳
發(fā)表于 2025-3-22 02:45:05 | 只看該作者
Use of Bisphosphonates in Oncology,ications associated with bone metastases, thus maintaining and restoring patients’ mobility and function and reducing pain. The mechanism of bisphosphonates action and the use of these drugs in breast, prostate, lung, kidney, bladder, and thyroid cancers are described.
地板
發(fā)表于 2025-3-22 05:44:56 | 只看該作者
Book 2012s. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today‘s oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as t
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發(fā)表于 2025-3-22 11:07:38 | 只看該作者
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發(fā)表于 2025-3-22 16:50:47 | 只看該作者
https://doi.org/10.1007/978-3-642-99379-4f ONJ, whereas CT and MRI are adequate in evaluating bone involvement, in addition to offering the advantage that destructive processes can be seen at high resolution. Functional imaging, especially bone scintigraphy, provides a tool for the detection of early stages of ONJ.
7#
發(fā)表于 2025-3-22 18:03:13 | 只看該作者
https://doi.org/10.1007/978-3-642-99379-4is of BIONJ may represent a microbial-biofilm-mediated infectious disease in the context of BP therapy. Accordingly, biofilms are a potential target for clinical therapy, with specific antibiofilm agents used in the treatment and prevention of BIONJ.
8#
發(fā)表于 2025-3-22 22:19:35 | 只看該作者
Use of Bisphosphonates in Hematology,tting adverse outcome. This chapter reviews the current theories explaining the mechanism for this complication. We report evidence for the use of BPs in hematologic diseases and provide recommendations to guide the clinical practice of treating bone disease in hematologic patients.
9#
發(fā)表于 2025-3-23 03:47:13 | 只看該作者
Instrumental Diagnosis,f ONJ, whereas CT and MRI are adequate in evaluating bone involvement, in addition to offering the advantage that destructive processes can be seen at high resolution. Functional imaging, especially bone scintigraphy, provides a tool for the detection of early stages of ONJ.
10#
發(fā)表于 2025-3-23 06:51:54 | 只看該作者
Microbiological Aspects of Osteonecrosis of the Jaw,is of BIONJ may represent a microbial-biofilm-mediated infectious disease in the context of BP therapy. Accordingly, biofilms are a potential target for clinical therapy, with specific antibiofilm agents used in the treatment and prevention of BIONJ.
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