Titlebook: Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites; Giancarlo Lancini,Rolando Lorenzetti Book 1993 Springer Science+Bu

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ology of microbial secondary metabolites. Generalbiology,biosynthesis, the search for novel metabolites, andtechniques forstrain improvement are all discussed to provideundergraduate andgraduate students with a concise, readable overviewof the field.978-1-4757-9524-0978-1-4757-9522-6

PON

Some Properties of Phytochrome,ght microbial metabolites that at low concentrations inhibit the growth of other microorganisms. The reason for this preference is that this class of natural products is clearly identified by its origin and by its biological activity. Nevertheless, some of the expressions used in the definition need further clarification.

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Intracellular Localization of Phytochrome,accepted. Some of these mechanisms are specific for antibiotic production but, remembering that secondary metabolism is a form of differentiation, it is not surprising that its regulation often falls under more general systems of control governing other forms of differentiation, such as the sporulation process or the formation of aerial mycelium.

使成整體

Phytochrome and Flower Initiation, Properties such as the membrane transport (and hence the penetration into bacterial cells), absorption and distribution throughout the body, and susceptibility to the action of inactivating enzymes can be drastically influenced by modifications of the original molecule.

BUST

生命

The Search for New Bioactive Microbial Metabolites, screening programs, were established by Waksman at Rutgers State University in the early 1940s. They are still valid today and are applied in many academic and industrial research laboratories all over the world.

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Biosynthesis of Secondary Metabolites, great variety of chemical structures, the biological reactions involved in the biosynthesis of most secondary microbial metabolites can be grouped in a limited number of biosynthetic pathways. In this chapter we give a short description of these pathways, and summarize the methods commonly used for their identification.