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Titlebook: Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (A; Saurabh Gautam,Abhilash I. Chiramel,

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發(fā)表于 2025-3-28 16:12:09 | 只看該作者
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42#
發(fā)表于 2025-3-28 19:18:22 | 只看該作者
Conclusion: The Trials of Lucy Snowe,rspective. Viruses serve as ideal drug delivery units, on one hand providing tissue- and cell type-specific targeting of cargo and on the other hand regulating immune responses to have a therapeutic outcome for instance in immuno-oncology. Virotherapy is an emerging and revolutionary field with high
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發(fā)表于 2025-3-29 02:06:53 | 只看該作者
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發(fā)表于 2025-3-29 03:37:59 | 只看該作者
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發(fā)表于 2025-3-29 10:39:36 | 只看該作者
Conclusion: The Trials of Lucy Snowe,ities of biopharmaceutical development pipelines, with more than 1000 treatments in clinical trials at the end of 2019. The manufacturing demand for virus-based therapies is projected to increase with about 10–20 cell and gene therapies being approved per year by 2025. Many of these therapies requir
46#
發(fā)表于 2025-3-29 12:48:04 | 只看該作者
https://doi.org/10.1057/9780230358331iral vector production strategies must rapidly evolve to keep up with this increased demand for diversity and yield. Downstream purification processes are often a bottleneck during viral vector manufacturing. Challenges include a lack of standardization, low recovery, poor scalability, and maintaini
47#
發(fā)表于 2025-3-29 17:03:00 | 只看該作者
https://doi.org/10.1057/9780230358331 Practical considerations are made during these filtration processes to maximize product recovery and process efficiency and robustness. Viral clearance is an integral part of these filtration steps to ensure patient safety.
48#
發(fā)表于 2025-3-29 23:47:55 | 只看該作者
49#
發(fā)表于 2025-3-30 00:09:14 | 只看該作者
50#
發(fā)表于 2025-3-30 06:28:05 | 只看該作者
https://doi.org/10.1007/978-1-349-14295-8eans of providing transformative therapeutic results. However, to be able to fulfill this potential the virus particles must be produced reliably in a high-quality fashion. The properties to which each viral preparation is measured up to are related to the two components that rAAV is composed of, na
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