Titlebook: Biophysical approaches to translational control of gene expression; Jonathan D. Dinman Book 2013 Springer Science+Business Media New York

Functional

https://doi.org/10.1007/978-94-007-5491-1 decades toward this goal. Cross-linking and footprinting were among the first methods used to probe the interactions of translation factors with the ribosome and the structures of ribosomal complexes. Since publication of the first high-resolution structures, these methods have continued to provide

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Prosaic

Ionizing Radiation and the Endothelium,olecular assemblages. The use of those techniques has proven to be crucial in deciphering mechanisms of translation. To date, essentially every step of protein synthesis has been probed by rapid kinetic techniques. Understanding the functional mechanisms required specific methods to determine the ti

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Normal Tissue TNM Toxicity Taxonomy,mine molecular structure. Here, we review the use of NMR and SAXS for the structural analysis of RNA molecules, with a focus on RNAs involved in translational control. Practical considerations, experimental requirements, and data analysis are discussed. We also review a recently developed hybrid app

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Neurological Complications in Adultss. By manipulating assay design, it is possible to extract equilibrium binding constants down to the low or even sub-nanomolar range, as well as measure reaction on- and off-rates, changes in enthalpy and entropy, and RNA-binding site size. These tools are invaluable for comparing and contrasting po

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geriatrician

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Neurological Complications in Childrendiscovery. The discovery of a broad range of important biological processes involved by RNA has increased the importance of RNA as a new drug target. To apply structure-based virtual screening methods to the discovery of RNA-binding ligands, many RNA 3D structure prediction programs and optimized do

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