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Titlebook: Biopharmaceutical Manufacturing; Progress, Trends and Ralf P?rtner Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusi

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發(fā)表于 2025-3-21 18:52:43 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Biopharmaceutical Manufacturing
期刊簡稱Progress, Trends and
影響因子2023Ralf P?rtner
視頻videohttp://file.papertrans.cn/189/188317/188317.mp4
發(fā)行地址Comprehensive review of manufacturing aspects for biopharmaceuticals, including cell and gene therapy.Brings together the knowledge and experience of leading international experts from academia and in
學(xué)科分類Cell Engineering
圖書封面Titlebook: Biopharmaceutical Manufacturing; Progress, Trends and Ralf P?rtner Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusi
影響因子.This volume “Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges” is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation..The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin′s and facility design. The kn
Pindex Book 2023
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書目名稱Biopharmaceutical Manufacturing影響因子(影響力)




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Advances in Characterization of Industrial Bioreactors for Cell Culture Process of uses. This book chapter provides an overview of the main characterization methods for aerated stirred tank reactors in the context of cell culture processes. The methods described include mechanical power input, volumetric mass transfer, flow field, and mixing characterization. Examples are give
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Continuous Bioprocessing for Downstreamreasing equipment footprint and increase equipment utilization. For the interested reader this chapter provides an overview over the main developments in continuous downstream processing of biopharmaceuticals and introduces the main unit operations such as continuous chromatography, continuous filtr
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發(fā)表于 2025-3-22 14:38:53 | 只看該作者
Towards Digital Twin for Biopharmaceutical Processes: Concept and Progressopharmaceutical manufacturing field. The realization of DT could help reduce cost, improve productivity, maintain high and constant product quality, and meet Quality-by-Design (QbD) guidelines. Nonetheless, the development of DT is still at its infancy stage and an integrated DT in biopharma is rare
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Production of Complex Proteins in Plants: From Farming to Manufacturingl host cells cannot produce complex biopharmaceuticals that require defined oligomerization or specific glycosylation profiles, and mammalian cells are unsuitable for the production of toxic proteins. These issues are readily overcome by plant cell cultures, which have the machinery required for com
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Biopharma 4.0 for Biologics Manufacturing Under Pandemic Constraintslow doses and less side effects. Biopharma 4.0 relates to the fourth industrial revolution based on digitalization. Digitalization has reached biopharmaceutical industry along the whole development and value chain. Biologics manufacturing of such complex three-dimensional molecules in correct foldin
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