| 期刊全稱(chēng) | Biomolecular Imaging at High Spatial and Temporal Resolution In Vitro and In Vivo | | 影響因子2023 | Thomas Harry Sharp | | 視頻video | http://file.papertrans.cn/189/188257/188257.mp4 | | 發(fā)行地址 | A concise primer to a variety of both light and electron microscopy techniques allows the reader to make an informed decision regarding which one will be best for their own research.An expansive intro | | 學(xué)科分類(lèi) | Springer Theses | | 圖書(shū)封面 |  | | 影響因子 | As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom‘s inventions and are described in this thesis. | | Pindex | Book 2014 |
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