Titlebook: Biomarkers in Cancer Therapy; Liquid Biopsy Comes Hideaki Shimada Book 2019 Springer Nature Singapore Pte Ltd. 2019 Cancer screening.Exoso

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978-981-13-7297-1Springer Nature Singapore Pte Ltd. 2019

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Liquid Biopsy in Hepatocellular Carcinomarly stage, effective treatment options, and prevention of recurrence. Recently, liquid biopsies, such as circulating tumor cells, circulating tumor DNA, and microRNA, have accumulating evidence that is useful for these needs..In this review, we summarize the current advance of liquid biopsies and discuss the perspective.

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Liquid Biopsy Diagnostics Using Extracellular Vesiclesthers. Recent studies indicated that cancer-associated EVs play pivotal roles in constructing favorable microenvironments for cancer cells through communication with various surrounding or remote cells. In fact, they induce immunosuppression, angiogenesis, and epithelial-mesenchymal transition (EMT)

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Cell-Free DNAells is termed circulating tumor DNA (ctDNA). Despite the low levels of ctDNA in normal cfDNA, advances in digital polymerase chain reaction (PCR) and next-generation sequencing (NGS) technologies have led to significant improvements in the sensitivity and specificity of variant detection. As a resu

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Serum Angiogenic Factors as Cancer Biomarkerstment is applied for such angiogenic tumors, many patients suffer from progressive disease and/or rapid recurrence even after multimodal treatment. Serum angiogenic factors could be useful for predicting malignant potential and monitoring treatment response in such angiogenic tumors. Here, a compreh

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Specifics 1: Head and Neck Cancer and Esophageal Cancerly attributed to the absence of specific symptoms during early-stage cancer and the lack of reliable biomarkers. The identification of biomarkers has the potential to aid early diagnosis and prediction of recurrence and therapeutic efficacy. Biomarkers can also enable the improvement of long-term pr

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Biomarkers in Gastric Cancerincrease during early-stage carcinogenesis, so they are not useful for early diagnosis of gastric cancer. In the outpatient center after gastrectomy, however, simple biomarkers are still convenient, and serum RNA (microRNA and long noncoding RNA) biomarkers are newly emerging, as they exhibit higher

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