Titlebook: Biomarkers in Cancer; Victor R. Preedy,Vinood B. Patel Living reference work 20200th edition

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Breast Cancer: Serum TPS as a Biomarker,nformation and establishing patient responses to therapy. A main limitation of TPS is that it is not “organ specific,” which impedes diagnostic utility. Additionally, TPS levels are altered according to inflammation conditions, such as liver cirrhosis, ovulation, and menopausal status. Further clini

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CA 19-9 as a Serum Biomarker in Cancer, used most commonly as a biomarker in pancreatic cancer as a prognostic and predictive tool and less commonly in other malignancies. This chapter will focus mainly on utility of CA 19-9 in pancreatic cancer and biliary tract cancers.

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Cancer Cardiotoxicity and Cardiac Biomarkers,ike targeted therapy (i.e., trastuzumab) or angiogenesis inhibitors are all associated with some form of cardiac toxicity: while targeted drugs may induce a reversible damage, angiogenesis inhibitors have a prothrombotic activity, which leads to a high incidence of thromboembolic events..Patients we

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Carcinoembryonic Antigen-Family Cell Adhesion Molecules (CEACAM) as Colorectal Cancer Biomarkers,tigen (CEA) is the biomarker most frequently used in colorectal cancer. It is effective in the surveillance of colorectal cancer patients and in monitoring the efficacy of therapy, whereas it is less useful in colorectal screening. Recent studies indicate that also CEA-related proteins (CEACAMs) are

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Centrosome Amplification as Biomarkers in Bladder Cancer Using Touch Biopsy and Bladder Washing Cytand Ki-67 (MIB-1) overexpression and UroVysion (multicolor fluorescence in situ hybridization kit for detecting copy number aberrations in chromosomes 3, 7, and 17, and the 9p21 locus), are promising for predicting disease progression and tumor recurrence in NMIBC. Further validation with a prospect

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Circulating Biomarkers in Hodgkin Lymphoma,Although PET/CT is currently the most important tool used, interpretation is imperfect with low false-negative rates countered by high false positives. Furthermore, PET/CT is unavailable in many rural or underprivileged centers and, even in the most advantaged centers, is impractical for frequent te

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Circulating Tumor Cells as Biomarkers in Cancer,aggressive adjuvant therapy. Furthermore, various studies have shown that temporal monitoring of CTCs can be used to evaluate patient responses to therapy and to detect genetic and phenotypic changes to tumors in real time, allowing more effective treatment guidance.

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