Titlebook: Biology of Renal Cell Carcinoma; Ronald M. Bukowski,James H. Finke,Eric A. Klein Conference proceedings 1995Latest edition Springer-Verlag

Aspiration

Classification of Renal Cell Carcinoma Based on Morphologic and Cytogenetic Correlations introduced the term hypernephroma in 1883. Grawitz postulated a hypernephrogenic origin of renal cancers, whose cells exhibit a light cytoplasm. During recent decades it has become customary to view renal cell carcinoma as a complex entity. Despite support for this idea by the World Health Organiza

COMA

Molecular Cytogenetic Stratification of Renal Cell Tumorsof the patients have metastatic disease at the time of diagnosis and one-third of the remainder will develop distant metastases during the postoperative course. The most effective therapy for RCC localized to the kidney is surgery, whereas a metastatic tumor is practically incurable. The overall res

Triglyceride

Oncogenes in Renal Cell Carcinomaf human cancers. This is consistent with the “multistep carcinogenesis” hypothesis, and accounts for the exponential relationship between the incidence rate and the age of onset of human cancers (1,2). Two types of genes have been implicated in the development of human cancers: oncogenes and tumor s

Calculus

Occipital-Lobe

The Cloning of Tumor Suppressor Genes from the Short Arm of Human Chromosome 3 that Play a Role in ta (RCC). In these tumors, deletions or non-reciprocal translocations resulting in the loss of short arm material have been demonstrated in a majority of cases (1,2). At the molecular level, loss of 3p heterozygosity has corroborated these cytogenetic changes (2–4). The introduction of a normal chrom