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Titlebook: Biology of Aging; Robert Zwilling,Cesare Balduini Book 1992 Springer-Verlag Berlin Heidelberg 1992 Alzheimer.alzheimer‘s disease.biology.b

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樓主: Gram114
51#
發(fā)表于 2025-3-30 08:49:08 | 只看該作者
Spezielle VT-Implementationsprobleme,creased interest in the biology of aging and in the pathology of age-associated diseases. Among these, Alzheimer’s disease (AD) is the most frequent cause of dementia and as such already the fourth leading cause of death. Its pathological basis was defined by Alois Alzheimer in 1907 in a case report
52#
發(fā)表于 2025-3-30 16:15:59 | 只看該作者
53#
發(fā)表于 2025-3-30 16:44:32 | 只看該作者
54#
發(fā)表于 2025-3-30 20:47:46 | 只看該作者
Rechnerverbund Im Bildschirmtext,t in connective tissues (such as cartilage, skin, blood vessel wall) where the extracellular matrix is large and well developed. In these tissues, PGs represent the most important component of the interfibrillar ground substance and interact with collagen fibrils [1–3].
55#
發(fā)表于 2025-3-31 02:32:28 | 只看該作者
https://doi.org/10.1007/978-3-642-67978-0ge-related alterations of tissues, then arteriosclerosis seems to be an aging phenomenon [4, 11]. Since we are the only species which suffers from arteriosclerosis, it appears that this disease is a consequence of a generalized evolutionary development related to aging.
56#
發(fā)表于 2025-3-31 07:32:54 | 只看該作者
57#
發(fā)表于 2025-3-31 11:46:59 | 只看該作者
Heinz Burkhardt,Sigram Schindlerwhich uses nicotinamide-adenine dinucleotide (NAD) as substrate (for review, see [1]). The DNA-binding domain of the enzyme specifically binds to DNA single-or double-strand breaks, resulting in enzyme activation. Thus, treatment of cells with chemical or physical carcinogens induces a dose-dependen
58#
發(fā)表于 2025-3-31 14:39:42 | 只看該作者
Stand der Normung im CCITT, Ebenen 2–6d of variably differentiated cells that share a number of morphologic markers normally expressed by neurons and endocrine cells [3, 4]. In laboratory animals, the occurrence of neuroendocrine tumours, which is virtually null in young animals, shows an extraordinary increase with age [5, 6]. The reas
59#
發(fā)表于 2025-3-31 17:37:12 | 只看該作者
Heinz Burkhardt,Sigram Schindler the pigmentation of the culture changes, the peripheral hyphae (filamentous “cells” of a mycelium) become slender and undulate, and the formation of aerial hyphae is drastical reduced. Some days after the first occurrence of these morphological symptoms of aging, the culture stops growing and dies.
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