Titlebook: Biologics to Treat Substance Use Disorders; Vaccines, Monoclonal Ivan D. Montoya Book 2016 Springer International Publishing Switzerland 20

Cerumen

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Viral Gene Transfer of Enzymesa highly efficient cocaine hydrolase that reduces or prevents cocaine access to reward centers in the brain. A theoretical rationale for this approach will be presented first, followed by a brief survey of viral gene transfer in terms of risks and benefits from specific classes of agents that might

泄露

Adenovirus-Based Vaccines for the Treatment of Substance Use Disordersantibodies can bind to addictive drugs in the blood preventing them from crossing the blood–brain barrier, the development of anti-addictive drug vaccines can prevent the administered drugs from reaching their cognate receptors in the brain. Vaccine strategies against addictive drugs have included l

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Exploration of DNA Nanostructures for Rational Design of Vaccinesyet been fully realized in part due to insufficient immunogenicity of the small chemical compounds displayed on the vaccines. Over the past decade, extensive research effort, includi from modification of hapten linker structures and carrier proteins, addition of various adjuvants, and exploration of

headway

Ivan D. MontoyaCovers all aspects of vaccines and other biologics employed for treatment of substance use disorders.Discusses novel strategies to optimize the development and efficacy of biologics.Written and edited

Atheroma

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978-3-319-79451-8Springer International Publishing Switzerland 2016

遍及

Monoclonal Antibodiesn 1975. To make this discovery, they developed a lymphocyte fusion technique that allowed selection of monoclonal antibodies of refined specificity and affinity. They received a Noble Prize in Physiology or Medicine in 1984 for this breakthrough innovation.