| 期刊全稱 | Biological and Clinical Landscape of Meningiomas | | 影響因子2023 | Gelareh Zadeh,Roland Goldbrunner,Farshad Nassiri | | 視頻video | http://file.papertrans.cn/188/187489/187489.mp4 | | 發(fā)行地址 | Provides a comprehensive review of the current clinical and molecular landscape of meningioma research.Written by world-renowned experts in neurosurgery, neuropathology, radiology, radiation-oncology. | | 學(xué)科分類 | Advances in Experimental Medicine and Biology | | 圖書(shū)封面 |  | | 影響因子 | ."Meningiomas are tumors that originate from the arachnoidal cap cells of the leptomeninges. With an incidence rate of 8.36 per 100, 000 population, they are the most common primary central nervous system (CNS) tumors, accounting for a third of all cases.?The?World Health Organization (WHO) classification has traditionally categorized meningiomas into 15 different histopathological subtypes and three clinical grades.?Tumors are classified as WHO grades 1, 2 or 3 based largely on histopathological features such as mitotic activity, presence of brain invasion, and other atypical features. However, there is increasing recognition of the limitations of histopathology including but not limited to: confounding factors such as sampling bias in a heterogeneous tumor, and technical factors related to the experience of the grading pathologist. Even with careful histologic grading, there remains significant variability in recurrence rates within each tumor grade. As more studies have uncovered the molecular features of meningiomas, novel biological alterations have helped refine classification schemes that more accurately reflect patient outcomes. This book reviews the current state of knowle | | Pindex | Book 2023 |
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