Titlebook: Biological Aging; Methods and Protocol Trygve O. Tollefsbol Book 2007 Humana Press 2007 DNA.Evolution.Microarray.Mutation.Proteomics.Telome

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Techniques for Analysis of Biological Aging,des, a popular mode of studying biological aging has been the analysis of cells cultured in vitro that display cellular senescence. Current interest is also focused on models of senescence that include organismal aging such as aging of yeast and .. The number of techniques applied to biological agin

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Aging Cell Culture,ess is leading to the development of therapies that slow or ablate the adverse physiological and pathological changes associated with aging. It has been established that normal human diploid fibroblasts can proliferate in culture for only finite periods of time. Hayflick and Moorhead and others have

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Methods to Detect Biomarkers of Cellular Senescence,ogenic stimuli, in culture and most likely in vivo. Cellular senescence is characterized by an irreversible growth arrest and certain altered functions. Senescent cells in culture are identified by their inability to undergo DNA synthesis, a property also shared by quiescent cells. Several years ago